Astragalus and cancer. APS can limit the spread of cancer by influencing immune cells, promoting cell death, triggering cancer cell autophagy, and impacting Similar remarkable results, with similar critical caveats, were published for astragalus-containing formulas for colorectal cancer including improved quality of life. It demonstrates chemo-preventive effects by enhancing immune defenses against cancer and serves as an adjuvant to cancer treatments. Adding astragalus to standard platinum-based chemo reduced the risk of death as much as 38 percent at the one-year-mark, and 25 percent at two years. Preclinical studies indicate that APS exerts significant anti-liver cancer effects through multiple biological actions, including the promotion of apoptosis, inhibition of Summarizing the most recent advancements and ongoing applications of astragalus membranaceus in non-small cell lung cancer treatment. As an important component of traditional Chinese medicine, <i>Astragalus membranaceus</i> (AM) has demonstrated potential for multifacet … Many health benefits are overhyped and fake news, but these scientific studies about Chinese Astragalus membranaceus root are the real deal. Astragalus may benefit cancer patients in various ways. We have reported that Chinese herbs Astragalus polysaccharide (APS) can inhibit nuclear factor kappaB (NF-κB) activity during the development of diabetic nephropathy in mice. Astragaloside (As) has been demonstrated extensively to serve roles in a variety of tumor types, including glioma, lung cancer, colorectal cancer, breast cancer and cervical cancer, and has therefore been widely used in Traditional Chinese Medicine. Astragali Radix (Astragalus, Chinese name, Huangqi) sourced from medicinal plants Astragalus membranaceus and Astragalus membranaceus var. Author contributions Data curation: Jun Dong. Thus, they have become increasingly important in cancer immunotherapy. The chemicals in astragalus also […] At present, the FDA has authorized sipuleucel-T, which consists of blood cells enriched for APCs such as DCs. During one study, researchers investigated the effects of astragalus on cancer patients with compromised immune systems as a result of chemotherapy. Astragalus has been used for over two thousand years, and has been used by western herbalist practitioners since the 1880s. The root has been used for centuries in traditional Chinese Medicine (TCM). Astragalus Background: Astragalus polysaccharides (APS), natural plant compounds, have recently emerged as a promising strategy for cancer treatment, but little is known concerning their effects on breast cancer (BC) tumorigenesis. Background Cancer related fatigue (CRF) is a common and debilitating side effect among gynecologic cancer patients undergoing chemotherapy. Overall, this review aims to provide an insight into Astragalus membranaceus status in cancer therapy. The roots of Astragalus membranaceous or mongholicus are most commonly used for medicinal purposes. Many people have concerns about the potential interactions and contraindications between the concurrent use of botanicals and chemotherapy. mongoholicus (Leguminosae) has been listed in Chinese pharmacopoeia [10]. Astragalus polysaccharides (PG2), processed into a sterile powdery form, is the bioactive component of dried astragalus membranaceus (Chinese: Huang-Chi) roots, and elicits a broad spectrum of documented therapeutic effects, including modulation of the immune system. It has some anti . Astragalus polysaccharides (PG2), an immunomodulatory drug, has shown promise in relieving CRF. NF-κB plays important roles in genesis, growth, development and metastasis What is it? Astragalus (Astragalus membranaceus) is a type of flowering plant. | Find, read and cite all the research you Breast cancer, the most prevalent malignant tumor among women globally, remains a critical area of focus for researchers striving to refine therapeutic approaches. Astragalus at a glance Astragalus is a plant belonging to the legume (pea or bean) family. Ther … Jul 23, 2025 · Astragalus offers hope as a natural, supportive agent that may enhance chemotherapy’s effectiveness and reduce its side effects, ultimately improving the quality of life for cancer patients navigating their treatment journey. Astragalus has a long history of use in Chinese medicine for a variety of ailments and has Astragalus A natural product commonly used in traditional Chinese medicine herbal mixtures may help to improve quality of life, manage side effects, and treat certain cancers. At the same time, a systematic review and meta-analysis of Astragalus herbal medicine combined with chemotherapy for cervical cancer found that Astragalus improves the efficacy of treatment and reduces chemotherapy´s toxicity. 1 Astragalus is also used to treat various cancers. Methods This retrospective cohort study was performed at Astragalus root (Huang Qi) and Shiitake mushrooms (Lentinus edodes) are both considered medicinal foods and are frequently used in traditional Chinese medicine due to their anticancer and immunomodulating properties. This blog post explores its use in cancer, outlines the benefits and clinical studies as well as recommendations for its use. Astragalus polysaccharide or Astragalus membranaceus polysaccharides, extracted and purified from the dried roots of Astragalus membranaceus (belonging to the Fabaceae family), is a water-soluble PDF | The rising global morbidity and mortality rates of non-small cell lung cancer (NSCLC) underscore the urgent need for more effective treatments. As an important component of traditional Chinese medicine, Astragalus membranaceus Astragalus membranaceus (HUANG QI, HQ) is one of the most commonly used Chinese medicine in clinical practice, which is the dried rhizome of Astragalus membranaceus. It is most known for its ability to increase stamina and improve the immune system. The keywords included [“ Astragalus membranaceus ” or “ Huangqi ”] or [“ Astragalus ”] and [“tumor” or “cancer” or “immunity” or “immune”]. A majority of herbal supplements, including Astragalus membranaceus (astragalus) and formulas containing astragalus, are consumed based on their traditional use. In addition to its immune-stimulating effects, some studies have shown that it can reduce some chemotherapy side effects such as poor appetite, anemia, and fatigue. In view of the multiple functions of APS in immunotherapy and tumor microenvironment, a combination of APS and immunotherapy in cancer treatment has a promising prospect. S. Its root has been used in traditional Chinese medicine for centuries as an immune system booster and to prevent and treat various illnesses. However, the reliability of the available evidence remains elusive. It has become a buzzword of herbalists as it is one of the best of seven important adaptogenic herbs with a protective effect against chronic stress and cancer. Objectives: This study aimed to summarize the evidence on Astragalus membranaceus on cancer-related fatigue and quality of life in patients with cancer. Keywords: cancer immunotherapy, traditional Chinese medicine, astragalus polysaccharide, immune checkpoint inhibitors, DC vaccine Along with healing cancers, 6 Amazing Astragalus Benefits that can help you boost and maintain your health. In the context of Western medicine it is claimed to have The rising global morbidity and mortality rates of non-small cell lung cancer (NSCLC) underscore the urgent need for more effective treatments. Current therapeutic modalities—including surgery, radiotherapy, chemotherapy, and targeted therapy—face The University of Texas has shown that Astragalus seems to be an adaptogenic herb ’offering up’ viruses, bacteria and even cancer cells to be seen by the immune system. Astragalus membranaceus is widely used in many countries to treat cancer, but its efficacy and safety is uncertain. Astragalus contains bioflavonoids, choline and a polysaccharide, astragalan B, amongst other active ingredients. Astragalus Astragalus root has a long history of use in traditional Chinese medicine and is used for a variety of conditions. Astragalus benefits may include immune support, improved heart health, better blood sugar management in people with diabetes, stress relief, and more. Apr 10, 2025 · Current evidence suggests that Astragalus membranaceus is one of the most commonly used herbal medicines for cancer treatment, with its primary component, Astragalus polysaccharide (APS), demonstrating immunomodulatory effects. Learn more about Astragalus uses, effectiveness, possible side effects, interactions, dosage, user ratings and products that contain Astragalus. Current therapeutic modalities—including surgery, rad Current evidence suggests that Astragalus membranaceus is one of the most commonly used herbal medicines for cancer treatment, with its primary component, Astragalus polysaccharide (APS), demonstrating immunomodulatory effects. Breast cancer, the most prevalent malignant tumor among women globally, remains a critical area of focus for researchers striving to refine therapeutic approaches. Astragaloside, the major anti-cancer component of Astragalus mongholicus Bunge [Fabaceae], has been found to regulate tumor cell apoptosis, proliferation, invasion, and metastasis [Figure 2 and Table 1]. Proponents claim that when used by itself or in combination with other herbs, astragalus can benefit the immune system by aiding the body’s antibody responses, inhibiting tumour growth. Astragalus mem … Astragalus is a plant belonging to the Leguminosae family. Astragalus membranaceus reduces the side effects and improves the therapeutic actions of chemotherapy in cancer patients APS is more commonly used in a variety of tumors, including gastric cancer and colon cancer. Therefore, this systematic review and meta-analysis of studies intended to evaluate the therapeutic The ASCO Post’s Integrative Oncology series is intended to facilitate the availability of evidence-based information on integrative and complementary therapies sometimes used by patients with cancer. Language was limited to English and Chinese. Adaptogens are a class of natural substances that are believed to stimulate the body’s resistance to physical, environmental, and emotional stressors. However, further conclusive research is necessary. Same with cervical cancer, with remarkably reduced chemotherapy toxicity: less nausea and vomiting, less hair loss, less nerve damage, and less liver and kidney toxicity. Read more Herbs for cancer treatment? Can herbs be used alongside conventional cancer treatment? These are the most common questions asked by cancer patients. 43 Cheng et al also conducted a systematic review and meta-analysis on the combination of Astragalus in the treatment Astragalus is the main component for treating Qi deficiency syndrome among various prescriptions. These polysaccharides have shown antitumor effects and are considered safe. Alex Speers ND, MS Astragalus, known as Huáng Qí in Chinese, is a flowering plant that is native to parts of China, Mongolia, and Korea. According to the 2020 Global Cancer Statistical Report, cancer is the second leading cause of death globally, with an increase in incidence in recent years (1, 2). This study aimed to evaluate the effectiveness of PG2 in managing CRF in gynecologic cancer patients. Astragalus polysaccharide (APS) derived from A. With cancer deaths increasing, the initiation, pathophysiology and curative management of cancer is receiving increasing attention. APS can limit the spread of cancer by influencing immune cells, promoting cell death, triggering cancer cell autophagy, and Review the research on astragalus’s effectiveness in managing side effects, improving cancer treatment outcomes, optimizing body terrain and more. The filter process was firstly done by search engine of the website which screened out 422 articles. It is also known as Huang Qi in Chinese traditional medicine. Be in the know! Outcome Astragalus membranaceus has demonstrated the ability to modulate the immune system during drug therapy making the patient physically fit and prolonged life. Among its diversified clinical applications, the potential use of this herb and its chemical const … Astragalus is a medicinal herb used in Tradiaitonal Chinese Medicine for centuries. Jul 11, 2023 · Astragalus is used in Traditional Chinese Medicine formulas to increase stamina, strength, and vitality. It has been used in cancer care mainly to reduce the severity of side effects, such as nausea, vomiting, fatigue, and immune suppression, from chemotherapy. Used today to boost immune function, prevent cancer, improve memory, & even shrink tumors. Astragalus is considered an adaptogen. Methods: We obtained breast Astragalus is a plant in the legume family, native to Asia. Therefore, we chose Astragalus as an intervention and systematically analyzed the therapeutic effect of Astragalus-containing prescription for CRF. Also known as milk vetch or huangqi, Astragalus is one of the most commonly used herbs in Traditional Chinese Medicine (TCM) for conditions where there is a deficiency of qi. This fact sheet provides basic information about astragalus—common names, usefulness, and safety, and resources for more information. Traditional therapies such as surgery and chemoradiotherapy are often accompanied by suppression of host immunity, which increase the risk of metastasis. In addition, DC vaccines have been proven to be effective in ovarian cancer, liver cancer, lung cancer, melanoma, and glioblastoma immunotherapy in vivo. Lung cancer is the leading cause of cancer death in the U. One of them are used in clinical trials to overcome cancer related fatigue. Background: Cancer-related fatigue is the most common complication in patients. Astragalus root is a powerful non-toxic herb. The rising global morbidity and mortality rates of non-small cell lung cancer (NSCLC) underscore the urgent need for more effective treatments. Malignant tumors are the primary reason for chronic noninfectious disease-related deaths and are the chief obstacle to a better life Astragalus is a herb that may have a range of health benefits. Abstract Astragalus polysaccharide (APS) derived from A. Learn about integrative oncology expert use of astragalus when caring for people with cancer. Among these botanical herbs, astragalus is one of the most used and discussed in oncology. Scientists examined the effects of astragalus among patients with cancer-related fatigue. Flavonoids from Astragalus complanatus (FAC) could inhibit the proliferation of breast cancer cells in a dose-dependent manner and suppress the cancer cell invasion in vitro, while in vivo administration of FAC increased the survivability of xenografted nude mice models of breast cancer [55]. Oct 1, 2021 · The natural phytoconstituents of this plant formononetin, astragalus polysaccharide, and astragalosides which show high potential anti-cancerous activity are studied and discussed in detail. membranaceus plays a crucial role in traditional Chinese medicine. Astragalus polysaccharides (APS), bioactive compounds derived from Astragalus membranaceus, have emerged as promising natural agents in the treatment of hepatocellular carcinoma, a leading cause of cancer-related mortality. Astragalus membranaceus is a major medicinal herb commonly used in many herbal formulations in the practice of traditional Chinese medicine (TCM) to treat a wide variety of diseases and body disorders. Patients taking the astragalus supplements experienced a faster recovery and improved survival rates. Astragalus extract exerts anti-inflammatory, pro-apoptotic, antioxidant effects, and activates specific neural pathways in the treatment of these conditions. Astragalus supplements are available Particularly, the Astragalus-containing Chinese herbal prescriptions are frequently combined with radiotherapy for lung cancer in clinic. Learn more here. g7sf69, jb9eg9, nzyzk6, bwg1u2, ay7jh, 9ovv4, quskbz, xd6s8, zkil9, x1qei,